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Center for Pharmacy Innovation and Outcomes


Medications are a primary therapeutic option for patients. Despite advances in treatments and growing evidence supporting best use, gaps in care related to medication use remain, resulting in substantial patient burden (cost, morbidity and mortality) and economic waste in an already stretched health care system. Careful evaluation of medication use within the real-world setting is an essential component of understanding gaps in medication therapy, the underlying reasons for these gaps and the impact of these gaps on patient care.

With a fuller understanding of the problem, the Center for Pharmacy Innovation and Outcomes (CPIO) aims to address medication gaps in care, leverage a highly evolved health IT infrastructure, apply robust data including patient-reported information, a growing genomic reservoir, and deploy trained and highly skilled clinical pharmacists. The CPIO is equipped to take advantage of the integrative health care environment at Geisinger and study the real-world effects of medications and the impact of provision of health services.

The CPIO is focused on translational outcomes and health care redesign across the following areas of interest:pharmacy services, pain and addiction management, medication adherence and safety, specialty/biologics, applied pharmacogenomics, pharmacoeconomics and outcomes, and population health.





Postdoctoral Fellows

  • Jones, Laney, PharmD, MPH
  • Pulk, Rebecca, MS, PharmD, MS 


Selected Initiatives & Projects

Pharmacy Services

Improving Transitional Care through Communication between Pharmacists
In an effort to cut the rate of preventable rehospitalizations for patients discharged from Geisinger facilities, researchers in the CPIO have initiated a study supported by the National Association of Chain Drug Stores Foundation evaluating the impact of pharmacist transmission of information from the inpatient to the outpatient setting on patient outcomes.

Pharmacist-led Familial Hypercholesterolemia Multidisciplinary Clinic
In collaboration with primary care providers and specialists at Geisinger, we are developing a patient and family member care process for our patients diagnosed with familial hypercholesterolemia. The Medication Therapy Disease Management (MTDM) pharmacists are providing medication reviews and adjustments to help patients reach their treatment goals.

Pain and Addiction Management

Medication Take-Back
Within the past 15 years, the United States has witnessed a 300 percent increase in the incidence of deaths due to prescription drug overdose. A common source of prescription drugs is the medicine cabinet where unused, unneeded or expired medications account for a large component of the abused supply. In partnership with the Pennsylvania District Attorney's Association, the Pennsylvania National Guard, regional law enforcement and local schools and universities, Geisinger is leading an effort to make available medication take-back boxes at convenient locations within the community. Our researchers in the CPIO are leading the effort and studying the effects of expanded boxes on public health.

Pain Management
Geisinger Health System opened a pharmacist-led Medication Therapy Disease Management (MTDM) Chronic Pain Clinic in 2012 to help patients better manage their pain and identify/prevent addiction. The multidisciplinary clinic is comprised of administrators, primary care and interventional pain physicians, pharmacists, registered nurses and social workers/addiction counselors. Our goal is to help patients decrease their pain so they can reach important life goals.

Medication Adherence and Safety

Having a complete, accurate medication list that is transparent to health care providers and the patient is the principal goal in designing MedTrue. In a multidisciplinary effort led in part by Michael Evans and Eric Wright, MedTrue is a comprehensive medication adherence database and web-based application intended to serve as a single source for medication reconciliation, adherence monitoring and patient engagement support to help improve primary and secondary adherence.


Optimizing High-Cost Biologic Treatments for Patients with Multiple Sclerosis
Patients with multiple sclerosis (MS) will receive reliable delivery of the best practices designed by an evidence-based care path based on disease severity to deliver on the promise of value-based care. In addition, a 360-degree view of every MS patient is needed to assess the impact and quality of this program. Payers will be confident that their health care spending is well-stewarded and delivering on outcomes and preventing exacerbations that is important to patients and families. The infrastructure developed to manage high-cost biologics for MS, including the data capture applications, analytics and health IT tools, will be built to be scalable and extensible to enable efficient spread of this program to other high-cost therapeutics across the Geisinger Health System.


Select Publications

  • Graham JH, Sanchez RJ, Saseen JJ, Mallya UG, Panaccio MP, Evans MA. Clinical and economic consequences of statin intolerance in the United States: results from an integrated health system. Journal of Clinical Lipidology. In press.  DOI:
  • Deitelzweig S, Evans M, Hillson E, Trocio J, Bruno A, Tan W, Lingohr-Smith M, Singh P, Lin J. (2016, Jan). Warfarin time in therapeutic range and its impact on healthcare resource utilization and costs among patients with nonvalvular atrial fibrillation. Curr Med Res Opin, 32(1):87-94.
  • Wright E, Darer J, Tang X, Thompson J, Tusing L, Fossa A, Delbanco T, Ngo L, Walker J. (2015, Oct). Sharing Physician Notes Through an Electronic Portal is Associated With Improved Medication Adherence: Quasi-Experimental Study. J Med Internet Res, 17(10).
  • Zachariah JP, McNeal CJ, Copeland LA, Fang-Hollingsworth Y, Stock EM, Sun FF, Song JJ, Gregory S, Tom JO, Wright EA, VanWormer JJ, Cassidy-Bushrow AE. (2015, Sep-Oct). Temporal Trends in Lipid Screening and Therapy Among Youth from 2002-2012. J Clin Lipidol, 9(5 Suppl):S77-87.
  • Nordstrom BL, Evans MA, Murphy BR, Nutescu EA, Schein JR, Bookhart BK. (2015, Mar). Risk of recurrent venous thromboembolism among deep vein thrombosis and pulmonary embolism patients treated with warfarin. Curr Med Res Opin, 31(3):439-447.
  • Fischer MA, Jones JB, Wright E, Van Loan RP, Xie J, Gallagher L, Wurst AM Shrank WH. (2015, Feb). A Randomized Telephone Intervention Trial to Reduce Primary Medication Nonadherence. Journal of Managed Care & Specialty Pharmacy, 2(21):124-31.




  • June 28, 2016: Eric Wright, PharmD, MPH, is interviewed on the new medication take-back program on WKOK’s On the Mark.
  • June 14, 2016: Geisinger’s Medication Therapy Disease Management (MTDM) Program named the recipient of the American Society of Health-System Pharmacists (ASHP) Award of Excellence for 2016. Read more
  • June 9, 2016: Pharmacist Nathan Sauers is key part of Geisinger's outpatient heart failure clinic team. Read more
  • May 20, 2016: Laney Jones, PharmD, MPH, post-doctoral fellow, wins the Foundation of the National Lipid Association's Hunninghake FH Abstract Award for outstanding achievement in the FH abstract competition.
  • April 14, 2016: Laney Jones, post-doctoral fellow, wins early career investigator award at HCSRN conference in Atlanta, GA. Read more
  • March 28, 2016: Geisinger receives grant from First Community Foundation Partnership to increase medication take-back in Lycoming County. Read more
  • March 18, 2016: Eric Wright, PharmD, MPH, shares testimony at a hearing with Senator Pat Toomey (R-PA) on reducing prescription drug abuse. Read more
  • March 2, 2016: Geisinger Health System Medication Therapy Disease Management Program is the recipient of the 2016 ASHP Award of Excellence. Read more
  • September 13, 2015: Eric Wright, PharmD, MPH speaks to new technologies that engage community pharmacists in care transitions. Read more
  • August 7, 2015: Michael Evans, RPh, wins Next Generation Pharmacist of the Year and Healthcare Systems Award.
  • June 16, 2014: Michael Evans, RPh, Describes Geisinger's Approach to MTM Programs by AJMCtv on YouTube. Watch


Contact Us

Center for Pharmacy Innovation and Outcomes
Geisinger Precision Health Center
190 Welles Street, Suite 128
Forty Fort, PA 18704

Geisinger Health System
100 North Academy Avenue
Danville, PA 17822