Research Programs
Molecular Neuroscience
Cardiovascular
Obesity, Metabolic Disease and Inflammatory Disease
Cancer
Genomics
Molecular Neuroscience
- George Argyropoulos - regulation of gene expression
- David Carey - extracellular matrix (ECM) modulation of peripheral nerve development
- Tooraj Mirshahi - regulation of potassium channels; regulation of ion channels by G protein signaling
- Janet Robishaw - cellular and molecular mechanisms of disease
- Nikolaos Tapinos - peripheral nerve development and injury response
Cardiovascular
- Gerda Breitwieser - calcium sensing receptor in cardiovascular disease
- David Carey - pathophysiology of abdominal aortic aneurysm
- Helen Kuivaniemi - genetics and genomics of abdominal aortic aneurysm
- Tooraj Mirshahi - animal models; heart failure; role of ion channels in cardiac function and disease
- Anne Moon - pathobiology of cardiac development; arrhythmia syndromes
- Janet Robishaw - animal models; heart failure; congenital heart problems; pathological angiogenesis
- Gerard Tromp - genetics of abdominal aortic aneurysm
Obesity, Metabolic Disease and Inflammatory Disease
- George Argyropoulos - obesity and diabetes; human and mouse models; regulation of appetite
- Catherine Berlot - G-protein modulation of T cell signaling
- Gerda Breitwieser - intestinal stem cells; peripheral regulation of obesity
- David Carey - extracellular matrix signaling in obesity
- Tooraj Mirshahi - leptin-meanocortin pathway; mechanism of weight loss, neuroendocrine control of metabolism, remission of T2D
- Anne Moon - role of Tbx3 in metabolism
- Janet Robishaw - animal models; resistance to hight fat diet induced obesity; adipose derived stem cells
Cancer
- Radhika Gogoi - endometrial cancer
- Anne Moon - role of Tbx3 in cancer and cell senescence
- Marius Sudol -
- Nikolaos Tapinos - cell migration in brain tumor metastasis
- WannianYang - Receptor tyrosine kinase signaling and cancer
Genomics
- George Argyropoulos - Genomics of obesity and diabetes
- Gerda Breitwieser - transcriptomics of vascular disease and obesity
- David Carey - incorporating genomic information into clinical practice; identification of genetic risk factors for AAA
- Helen Kuivaniemi - genomics of abdominal aortic aneurysms
- Tooraj Mirshahi - human variants associated with disease
- Anne Moon - identifying candidate genes for human cardiac malformations; applied pharmacogenomics
- Janet Robishaw - association of human genetic variants with clinical phenotypes
- Gerard Tromp - Bioinformatics and computational biology; electronic phenotyping using EMR data; genome-wide association; next-generation sequence analysis
- Wannian Yang - Genomic alterations and tumor genesis and progression
Weis Center for Research